Volunteering

Volunteering

We firmly believe that your role as study volunteers in clinical research is crucial in the advancement of medicine. Without your participation, new ways to prevent, diagnose, and treat diseases cannot be achieved. You are our medical heroes!

We're Here to Answer Your Questions

Our recruitment staff is available Monday through Friday to answer your questions. If you call outside these hours, leave a message, and your call will be returned. If you are interested in a study for healthy volunteers, please call 919-613-6244. If you are interested in a study for a specific medical condition, please call 919-613-6246. We are here to help!

contextual photo

We recognize how important you are to our mission and are committed to give back to you. When you participate in our studies, you will have the option to receive updates on study results and publications. You will dictate the frequency and method by which we reach out to you. This way, you will see quickly and directly the impact of your participation in accelerating new therapies to humans.

Volunteer Registry

If you are interested in being contacted for future research studies when it appears that you may be eligible based on the information you provide us, join our Research Volunteer Registry.


Additionally, you can view our other study opportunities below.

Crohn’s Disease Patients Needed for Drug Study

Men and women diagnosed with Crohn’s Disease are needed to participate in a research study to assess how a drug being investigated as a potential treatment for Crohn’s Disease affects the absorption, metabolism, and activity of other common medications. Eligible participants will be 18 to 65 years of age. Participation will involve 17 visits to the Duke Early Phase Clinical Research Unit, and 3 of these visits will be inpatient admissions that last for 2 consecutive nights each. Enrolled participants will receive financial compensation.

For more information

Please contact the Duke Early Phase Clinical Research Unit at 919-613-6246 or DCRIvolunteer@duke.edu.

Healthy Volunteers Needed

Healthy volunteers are needed to participate in a research study to determine the safety, tolerability, and activity of an investigational drug being developed as a potential treatment against malaria. Eligible participants will be men and women between the ages of 18 and 45 who do not smoke and do not use any prescription drugs. The study will involve a 2-night inpatient admission and 5 short follow-up visits afterward that will be completed within 2 weeks of finishing the inpatient admission. Enrolled participants will be compensated for their participation.

For more information

Please contact the Duke Early Phase Clinical Research Unit at 919-613-6244 or DCRIvolunteer@duke.edu.

Heart Failure Study for Patients with Preserved Ejection Fraction

Men and women diagnosed who have heart failure with preserved ejection fraction are needed to participate in a research study to determine the safety and efficacy of an investigational drug that is being developed as a potential treatment to improve the exercise and functional capabilities of people with heart failure. Eligible participants will have a confirmed diagnosis of heart failure and be at least 50 years old. Participation will involve 8 outpatient visits to the Duke Early Phase Clinical Research Unit. Enrolled participants will receive financial compensation.

For more information

Please contact the Duke Early Phase Clinical Research Unit at 919-613-6246 or DCRIvolunteer@duke.edu.

Heart Failure Study for Patients with Reduced Ejection Fraction

Men and women diagnosed with heart failure are needed to participate in a research study to determine the safety and efficacy of an investigational drug that is being developed as a potential treatment to improve cardiac function in people with heart failure. Eligible participants will have a confirmed diagnosis of heart failure and be at least 18 years old. Participation will involve 4 outpatient visits to the Duke Early Phase Clinical Research Unit. Enrolled participants will receive financial compensation.

For more information

Please contact the Duke Early Phase Clinical Research Unit at 919-613-6246 or DCRIvolunteer@duke.edu.

Investigational Drug Study for Children or Adults with Pompe Disease

Adults and children who are at least 3 years old are needed to participate in a research study to assess the safety and effectiveness of an investigational drug that is being developed as a potential treatment for Pompe Disease. Eligible participants will be Pompe Disease patients who have not yet been treated with enzyme replacement therapy. Participation will require biweekly infusion visits at the Duke Early Phase Clinical Research Unit for approximately 3 years. Compensation is provided to enrolled participants.

For more information

Please contact study coordinator Wan Lan Liang at 919-668-0972 or wan.liang@duke.edu.

Liver Cirrhosis Patients Needed

Men and women who are diagnosed with cirrhosis are needed to participate in a research study that will assess the effects of an investigational drug on people with cirrhosis compared to study volunteers with normal liver function. Eligible participants will have a confirmed diagnosis of cirrhosis and be between 18 and 70 years old. Participation will involve 5 outpatient visits and 1 inpatient admission to the Duke Early Phase Clinical Research Unit. Enrolled participants will receive financial compensation.

For more information

Please contact the Duke Early Phase Clinical Research Unit at 919-613-6244 or DCRIvolunteer@duke.edu.

Research Study for Patients with Myasthenia Gravis

Men and women diagnosed with generalized myasthenia gravis are needed to participate in a research study for an investigational drug that is being developed as a potential treatment for MG. The study will examine the effectiveness of the drug in treating the symptoms of MG when it’s administered on an every-other-week basis. Eligible volunteers will be age 18 or older, have received a diagnosis of generalized myasthenia gravis, and who have not used a biologic drug in the past year. Study participation will last approximately 4 months and enrolled participants will receive compensation.

For more information

Please contact the Duke Early Phase Clinical Research Unit at 919-613-6246 or DCRIvolunteer@duke.edu.

Study Needs Volunteers with Lower Back Pain

Volunteers who are currently experiencing lower back pain are needed to participate in a research study that will assess the feasibility of using activity and physical resilience measures to determine pain severity and how it affects functional ability. Eligible participants will be men and women between the ages of 60 and 85 who have been experiencing lower back pain for the past 3 months or longer. Participation will involve 1 outpatient visit to the DEPRU and the collection of 3 blood samples. Enrolled participants will receive financial compensation.

For more information

Please contact the Duke Early Phase Clinical Research Unit at 919-613-6246 or DCRIvolunteer@duke.edu