Andrew Krystal

Andrew Krystal

Andrew Krystal, MD

Co-Director, Neurosciences Medicine Research Program
Professor of Psychiatry and Behavioral Sciences



Dr. Krystal is co-director of the DCRI's Neurosciences Medicine (NSM) research program, director of the Duke Sleep Research Program, and clinical director of the Brain Stimulation Program, as well as a professor in the Department of Psychiatry and Behavioral Sciences

Krystal's research aims are to better understand the pathophysiology of sleep disorders and mood disorders and to develop improved treatments for these conditions. He is the overall principal investigator of the National Institute of Mental Health-funded New Experimental Medicine Studies: Fast-Fail Trials in Mood and Anxiety Spectrum Disorders (FAST-MAS). This established network of clinical trial sites focuses on identifying and testing promising pharmacologic interventions for the treatment of mood and anxiety spectrum disorders. Fast-Fail Trials include first-in-human, proof-of-clinical-mechanism, and proof-of-concept trials in adults.

Krystal forges an important bridge linking the expertise and resources of the DCRI in multicenter clinical trials with the strong expertise in translational neuroscience and intervention-development research within the Department of Psychiatry and Behavioral Sciences.