Daniel Mark


Daniel B. Mark, MD, MPH

Director, Outcomes Research
Professor of Medicine, Cardiology




Dr. Mark, a professor of medicine and clinical cardiologist, is a renowned expert on outcomes, quality of life, and health economics research. Mark has authored more than 250 peer-reviewed publications and currently holds multiple leadership positions including: Vice Chief, Cardiology Division, Duke University Medical Center (DUMC); Co-Director, Outcomes Research and Assessment Group, Duke Clinical Research Institute (DCRI); Co-Director, Cardiac Care Unit, DUMC; Professor of Medicine, DUMC; and Editor, American Heart Journal. Mark directs a number of cost-effectiveness analyses for ongoing clinical trials including the NHLBI-sponsored OAT (Occluded Artery Trial), the NHLBI-sponsored STICH (Surgical Treatment for Ischemic Heart Failure), and the NHLBI-sponsored ADEPT (ADvanced Elements of Pacing Randomized Controlled Trial). Mark is the principal author of the Agency for Health Care Policy and Research (AHCPR) Unstable Angina Guidelines, a co-author of the American College of Cardiology (ACC) Guidelines on Exercise Testing, and a co-author of the ACC Coronary Stent Consensus Guideline. In 2009, Mark received the ACC Distinguished Scientist Award for his outstanding research and quantitative methodology contributions.

Mark's major research interests include medical economics and quality of life outcomes, outcomes research, and quality of medical care. His clinical interests include intensive cardiac care, patients with acute myocardial infarction and unstable angina, and consultative cardiology.