Volunteering

Volunteering

We firmly believe that your role as study volunteers in clinical research is crucial in the advancement of medicine. Without your participation, new ways to prevent, diagnose, and treat diseases cannot be achieved. You are our medical heroes!

We're Here to Answer Your Questions

Our recruitment staff is available Monday through Friday to answer your questions. If you call outside these hours, leave a message, and your call will be returned. If you are interested in a study for healthy volunteers, please call 919-613-6244. If you are interested in a study for a specific medical condition, please call 919-613-6246. We are here to help!

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We recognize how important you are to our mission and are committed to give back to you. When you participate in our studies, you will have the option to receive updates on study results and publications. You will dictate the frequency and method by which we reach out to you. This way, you will see quickly and directly the impact of your participation in accelerating new therapies to humans.

Volunteer Registry

If you are interested in being contacted for future research studies when it appears that you may be eligible based on the information you provide us, join our Research Volunteer Registry.


Additionally, you can view our other study opportunities below.

Crohn’s Disease Patients Needed for Drug Study

Men and women diagnosed with Crohn’s Disease are needed to participate in a research study to assess how a drug being investigated as a potential treatment for Crohn’s Disease affects the absorption, metabolism, and activity of other common medications. Eligible participants will be 18 to 65 years of age. Participation will involve 17 visits to the Duke Early Phase Clinical Research Unit, and 3 of these visits will be inpatient admissions that last for 2 consecutive nights each. Enrolled participants will receive financial compensation.

For more information

Please contact the Duke Early Phase Clinical Research Unit at 919-613-6246 or DCRIvolunteer@duke.edu.

Heart Failure Study for Patients with Preserved Ejection Fraction

Men and women diagnosed who have heart failure with preserved ejection fraction are needed to participate in a research study to determine the safety and efficacy of an investigational drug that is being developed as a potential treatment to improve the exercise and functional capabilities of people with heart failure. Eligible participants will have a confirmed diagnosis of heart failure and be at least 50 years old. Participation will involve 8 outpatient visits to the Duke Early Phase Clinical Research Unit. Enrolled participants will receive financial compensation.

For more information

Please contact the Duke Early Phase Clinical Research Unit at 919-613-6246 or DCRIvolunteer@duke.edu.

Liver Cirrhosis Patients Needed

Men and women who are diagnosed with cirrhosis are needed to participate in a research study that will assess the effects of an investigational drug on people with cirrhosis compared to study volunteers with normal liver function. Eligible participants will have a confirmed diagnosis of cirrhosis and be between 18 and 70 years old. Participation will involve 5 outpatient visits and 1 inpatient admission to the Duke Early Phase Clinical Research Unit. Enrolled participants will receive financial compensation.

For more information

Please contact the Duke Early Phase Clinical Research Unit at 919-613-6244 or DCRIvolunteer@duke.edu.

Research Study for Patients with Myasthenia Gravis

Men and women diagnosed with generalized myasthenia gravis are needed to participate in a research study for an investigational drug that is being developed as a potential treatment for MG. The study will examine the effectiveness of the drug in treating the symptoms of MG when it’s administered on an every-other-week basis. Eligible volunteers will be age 18 or older, have received a diagnosis of generalized myasthenia gravis, and who have not used a biologic drug in the past year. Study participation will last approximately 4 months and enrolled participants will receive compensation.

For more information

Please contact the Duke Early Phase Clinical Research Unit at 919-613-6246 or DCRIvolunteer@duke.edu.

Antibiotic Study Enrolling Healthy Volunteers

Men and women in general good health are needed to participate in a research study to determine the safety, tolerability, and activity of an investigational combination of antibiotics that is being developed as a potential treatment against antibiotic-resistant bacterial infections. Eligible participants will be 18 to 45 years of age. Participation requires 2 outpatient visits and 1 inpatient admission to the Duke Early Phase Research Unit. Enrolled participants will receive financial compensation.

For more information

Please contact the Duke Early Phase Clinical Research Unit at 919-613-6246 or DCRIvolunteer@duke.edu.

Study for Potential Pneumonia Treatment Needs Healthy Volunteers

Healthy men and women are needed to participate in a research study to determine the safety, tolerability, and activity of an investigational drug that is being developed as a potential antibiotic to be used in the treatment of pneumonia and other bacterial lung infections. Eligible participants will be 18 to 45 years of age, non-smoking, and do not use any medications, with the exception of birth control. Participation requires 1 outpatient visit to determine eligibility and 1 inpatient admission to the Duke Early Phase Research Unit. Enrolled participants will receive financial compensation.

For more information

Please contact the Duke Early Phase Clinical Research Unit at 919-613-6246 or DCRIvolunteer@duke.edu.

A Study to Better Understand the Immune System Needs Healthy Volunteers

Healthy men and women are needed to participate in a research study to examine how people’s immune systems respond to the influenza virus after the administration of a “flu challenge.” Eligible participants will be men and women between the ages of 18 and 49 who are in general good health and have a BMI less than 35. Participation requires 5 outpatient visits and 1 inpatient admission to the Duke Early Phase Research Unit. Enrolled participants will receive financial compensation.

For more information

Please contact the Duke Early Phase Clinical Research Unit at 919-613-6246 or DCRIvolunteer@duke.edu.

A Drug Study Targeting the Microbiome Needs Volunteers with Ulcerative Colitis

Men and women with ulcerative colitis are needed to participate in a study of a drug that’s being developed to improve the digestive bacterial healthy of UC patients. Eligible candidates will be UC patients with a documented history of intolerance or failure to respond to immunotherapy. The study is done on an outpatient basis and will last for approximately 14 months. Enrolled participants will receive financial compensation.

For more information

Please contact the Duke Early Phase Clinical Research Unit at 919-613-6246 or DCRIvolunteer@duke.edu.

Investigational Therapy Study for People with Lower Back Pain

Men and women with mild-to-moderate back pain are invited to join a study that’s investigating the ability of an experimental non-drug therapy to lessen back pain for people who have been experiencing lower back pain for at least a month. Eligible participants will be 18 to 65 years of age. Participation requires 2 weeks of daily visits to the Duke Early Phase Research Unit. The visit weeks do not have to be back-to-back. Enrolled participants will receive financial compensation.

For more information

Please contact the Duke Early Phase Clinical Research Unit at 919-613-6246 or DCRIvolunteer@duke.edu.

Brain Injury Drug Study Needs Healthy Volunteers

Men and women in good health are needed to participate in a research study to determine the safety, tolerability, and activity of an investigational drug that is being developed as a potential treatment for brain inflammation that is associated with radiation therapy. Eligible participants will be 18 to 50 years of age. Participation requires 2 outpatient visits and 1 inpatient admission to the Duke Early Phase Research Unit. Enrolled participants will receive financial compensation.

For more information

Please contact the Duke Early Phase Clinical Research Unit at 919-613-6246 or DCRIvolunteer@duke.edu.