Volunteering

Volunteering

We firmly believe that your role as study volunteers in clinical research is crucial in the advancement of medicine. Without your participation, new ways to prevent, diagnose, and treat diseases cannot be achieved. You are our medical heroes!

We're Here to Answer Your Questions

Our recruitment staff is available Monday through Friday to answer your questions. If you call outside these hours, leave a message, and your call will be returned. If you are interested in a study for healthy volunteers, please call 919-613-6244. If you are interested in a study for a specific medical condition, please call 919-613-6246. We are here to help!

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We recognize how important you are to our mission and are committed to give back to you. When you participate in our studies, you will have the option to receive updates on study results and publications. You will dictate the frequency and method by which we reach out to you. This way, you will see quickly and directly the impact of your participation in accelerating new therapies to humans.

Volunteer Registry

If you are interested in being contacted for future research studies when it appears that you may be eligible based on the information you provide us, join our Research Volunteer Registry.


Additionally, you can view our other study opportunities below.

Asthma Patient Registry

The Duke Early Phase Clinical Research Unit is enrolling people with asthma into the American Lung Association's Asthma Clinical Research Center patient registry. If you have asthma and are interested in becoming involved in ALA-sponsored studies, you may participate in the registry regardless of your smoking status. Registry participants will play a role in furthering medical knowledge about the condition and be notified of any studies they might be qualified to participate in.

For more information

Please contact the Duke Early Phase Clinical Research Unit at 919-684-1554 or DCRIvolunteer@duke.edu.

Crohn’s Disease Patients Needed for Drug Study

Men and women diagnosed with Crohn’s Disease are needed to participate in a research study to assess how a drug being investigated as a potential treatment for Crohn’s Disease affects the absorption, metabolism, and activity of other common medications. Eligible participants will be 18 to 65 years of age. Participation will involve 17 visits to the Duke Early Phase Clinical Research Unit, and 3 of these visits will be inpatient admissions that last for 2 consecutive nights each. Enrolled participants will receive financial compensation.

For more information

Please contact the Duke Early Phase Clinical Research Unit at 919-613-6246 or DCRIvolunteer@duke.edu.

Drug Study for Patients with Post-Bariatric Hypoglycemia

Men and women between the ages of 18 and 65 who have been diagnosed with hypoglycemia following bariatric surgery are needed to participate in a research study to determine the safety and efficacy of an investigational drug that is being developed to potentially improve blood sugar control. Participation requires 8 outpatient visits during the course of 3 months. The study drug will be self-administered at home by study participants. Enrolled pariticipants will receive financial compensation.

For more information

Please contact the Duke Early Phase Clinical Research Unit at 919-613-6246 or DCRIvolunteer@duke.edu.

Drug Study for Skin Disease

Volunteers with various types of skin disease are needed to participate in a research study to assess the safety, tolerability, and activity of an investigational drug that is being developed as a potential treatment for plaque psoriasis, palmoplantar pustulosis, or hidradenitis suppurativa. Eligible participants will be men and women who are at least 18 years old and are not currently using a biologic agent to treat their skin disease. Participation involves 15 outpatient visits to the Duke Early Phase Clinical Research Unit over the course of approximately 5 months.

Study volunteers might receive a placebo rather than the active study drug. Compensation is provided to enrolled participants.

For more information

Please contact the Duke Early Phase Clinical Research Unit at 919-613-6244 or DCRIvolunteer@duke.edu.

Heart Failure Study for Patients with Preserved Ejection Fraction

Men and women diagnosed who have heart failure with preserved ejection fraction are needed to participate in a research study to determine the safety and efficacy of an investigational drug that is being developed as a potential treatment to improve the exercise and functional capabilities of people with heart failure. Eligible participants will have a confirmed diagnosis of heart failure and be at least 50 years old. Participation will involve 8 outpatient visits to the Duke Early Phase Clinical Research Unit. Enrolled participants will receive financial compensation.

For more information

Please contact the Duke Early Phase Clinical Research Unit at 919-613-6246 or DCRIvolunteer@duke.edu.

Heart Failure Study for Patients with Reduced Ejection Fraction

Men and women diagnosed with heart failure are needed to participate in a research study to determine the safety and efficacy of an investigational drug that is being developed as a potential treatment to improve cardiac function in people with heart failure. Eligible participants will have a confirmed diagnosis of heart failure and be at least 18 years old. Participation will involve 4 outpatient visits to the Duke Early Phase Clinical Research Unit. Enrolled participants will receive financial compensation.

For more information

Please contact the Duke Early Phase Clinical Research Unit at 919-613-6246 or DCRIvolunteer@duke.edu.

Investigational Drug Study for Children or Adults with Pompe Disease

Adults and children who are at least 3 years old are needed to participate in a research study to assess the safety and effectiveness of an investigational drug that is being developed as a potential treatment for Pompe Disease. Eligible participants will be Pompe Disease patients who have not yet been treated with enzyme replacement therapy. Participation will require biweekly infusion visits at the Duke Early Phase Clinical Research Unit for approximately 3 years. Compensation is provided to enrolled participants.

For more information

Please contact study coordinator Wan Lan Liang at 919-668-0972 or wan.liang@duke.edu.

Investigational Vaccine Study for C. Diff

Men and women who are at least 50 years of age are needed to participate in a research study to determine the safety and efficacy of an investigational vaccine that is being developed as a potential prevention for Clostridium difficile infection.

Eligible participants will be people for whom the following applies:

  • Have made 2 emergency room visits in the past 12 months; or
  • Have been hospitalized for at least 2 nights in the past 12 months; or
  • Have plans to stay in the hospital for at least 2 nights; or
  • Live in a nursing facility; or
  • Have made at least 10 outpatient hospital visits in the past 12 months; or
  • Have been prescribed or given antibiotics in the past 12 weeks

Participation will require 5 outpatient visits over the course of 7 months, and participants will receive 3 doses of the study vaccine or a placebo during the course of the study.

For more information

Please contact the Duke Early Phase Clinical Research Unit at 919-613-6246 or DCRIvolunteer@duke.edu.

Liver Cirrhosis Patients Needed

Men and women who are diagnosed with cirrhosis are needed to participate in a research study that will assess the effects of an investigational drug on people with cirrhosis compared to study volunteers with normal liver function. Eligible participants will have a confirmed diagnosis of cirrhosis and be between 18 and 70 years old. Participation will involve 5 outpatient visits and 1 inpatient admission to the Duke Early Phase Clinical Research Unit. Enrolled participants will receive financial compensation.

For more information

Please contact the Duke Early Phase Clinical Research Unit at 919-613-6244 or DCRIvolunteer@duke.edu.

Volunteers Needed for Bird Flu Vaccine Research Study

Men and women who are 19 years of age and older are needed to participate in a research study to determine the safety, tolerability, and activity of an investigational vaccine that is being developed to prevent a specific strain of the bird flu. Participation requires 12 study visits (7 clinic visits and 5 telephone visits) over the course of approximately 14 months. During the study, participants will receive 2 doses of study vaccine. Enrolled participants will receive financial compensation.

For more information

Please contact the Duke Early Phase Clinical Research Unit at 919-613-6244 or DCRIvolunteer@duke.edu.

Volunteers with COPD or Emphysema Needed

Men and women who have been diagnosed with COPD or emphysema are needed to participate in a research study to determine the potential effectiveness of an antihypertensive drug in the treatment of COPD or emphysema. Eligible participants will be at least 40 years old and have no plans to move out of the area for at least a year. Participation will require 7 or 8 visits to the Duke Early Phase Clinical Research Unit over the course of approximately one year. Compensation is provided to enrolled participants.

For more information

Please contact the Duke Early Phase Clinical Research Unit at 919-613-6244 or DCRIvolunteer@duke.edu.