COORDINATE-Diabetes Study RESULTS from ACC Scientific Sessions!

Bar graph comparing intervention outcomes between Usual Care (14.5%, shown in orange) and Intervention (37.9%, shown in blue) groups, with an absolute difference of 23.4%. Graph shows both unadjusted OR of 4.48 (p<0.001) and adjusted OR of 3.89 (p<0.001). Y-axis shows 'Participants prescribed all therapies (%)' ranging from 0 to 100.

COORDINATE-Diabetes aimed to identify strategies that improve the implementation and adoption of evidence-based therapies for patients with type 2 diabetes mellitus (T2DM) and atherosclerotic cardiovascular disease (ASCVD).

View Results Access Publication

About COORDINATE-Diabetes

COORDINATE-Diabetes was a cluster-randomized, controlled trial to assess the impact of a multifaceted educational intervention for healthcare staff on prescription rates for 3 groups of evidence-based therapies used to treat type-II diabetes and cardiovascular disease.

Sites randomized to the intervention received site-specific training and mentoring, as well as access to a suite of tools and resources to support intervention activities. See our Resources page for access to these tools.

The study enrolled 1049 participants at 42 cardiology clinics across the U.S. Participants were followed through review of clinic EHR data and telephone interviews for 6 to 12 months, depending on enrollment date, to collect information regarding medications and health outcomes.

The study was designed and conducted by the Duke Clinical Research Institute (Durham, NC). Funding was provided by Boehringer Ingelheim Pharmaceuticals, Inc. (BIPI) and Lilly USA, LLC.

Purple illustration of a clipboard with checkmarks and a cog symbolizing resources

Resources

COORDINATE-Diabetes tools and tips to support local implementation

Explore Resources

 

A purple illustration of a book symbolizing publications.

Publications

See what we’ve learned from the COORDINATE-Diabetes study

Explore Publications

Infographic showing the COORDINATE-Diabetes intervention components, displaying five key elements connected by arrows in a vertical layout, from access to specialists through assessment opportunities, with a resources link at the bottom.

Meet Our Team

Christopher Granger, MD
Principal Investigator
Read bio for Christopher Granger

Neha Pagidipati, MD, MPH
Co-Principal Investigator
Read bio for Neha Pagidipati

Renato Lopes, MD, PhD
Faculty Investigator
Read bio for Renato Lopes

Jennifer Green, MD
Faculty Investigator
Read bio for Jennifer Green

Adam Nelson, MD
Faculty Investigator
Read bio for Adam Nelson

Hussein Al-Khalidi, PhD
Faculty Statistician

Lisa Kaltenbach, MS
Principal Biostatistician

Laura Webb, BS, CCRP
Project Leader

Monica Leyva, MHA, RCIS
CRA, Intervention Lead

Lauren Wilverding, BS
Clinical Trials Assistant

Our Steering Committee

Vanita R. Aroda, MD
Associate Professor of Medicine
Harvard Medical School (Boston, MA)

Matthew A. Cavender, MD, MPH
Associate Professor of Medicine
University of North Carolina (Chapel Hill, NC)

Tanya Szesny Gaynor, MPAS, PA-C
Director, Strategy & Operations, Cardiometabolism and Respiratory
Clinical Development & Medical Affairs
Boehringer Ingelheim Pharmaceuticals, Inc

Julienne Kirk, PharmD, CDE, BCPS
Professor, Family and Community Medicine
Wake Forest University School of Medicine (Winston-Salem, NC)

Ildiko Lingvay, MD, MPH, MSCS
Professor of Medicine, Department of Internal Medicine/Endocrinology
UT Southwestern Medical Center at Dallas
(Dallas, TX)

Melissa Magwire, RN, MSN, CDE
Program Director, Cardiometabolic Center Alliance
Saint Luke’s Mid America Heart Institute
(Kansas City, MO)

Darren K. McGuire, MD, MHSc
Professor of Internal Medicine
UT Southwestern Medical Center and Parkland Health and Hospital System (Dallas, TX)

Jonathan Pak, PharmD, MBA
Director, Metabolism
Boehringer Ingelheim Pharmaceuticals, Inc.

Rodica Pop-Busui MD, PhD
Larry D. Soderquist Professor in Diabetes, Department of Internal Medicine
University of Michigan (Ann Arbor, MI)

Caroline Richardson, MD
Chair of Family Medicine
Warren Alpert Medical School / Care New England (Providence, RI)

Cagri Senyucel, MD, PhD
Senior Medical Director, Alliance Products
Eli Lilly and Company