DCRI Recruiting Studies

Collaboration among research sites, community partners, patients, their caregivers, and our study teams is critical to addressing current medical care challenges. We work with institutions around the world that are equally committed to safe, inclusive, and efficient clinical research.

We have provided a list of current opportunities for research partners and participants to engage with the DCRI, organized by therapeutic topic. By clicking on the study name, you can learn more about each opportunity.

Additional Resources for Patients and Study Participants

Cardiology

  • ARTEMIS: A Research Study to Look at How Ziltivekimab Works Compared to Placebo in People With a Heart Attack
  • BALANCED-HFA Phase III, Randomised, Double-blind Study to Evaluate the Effect of Balcinrenone/Dapagliflozin, Compared with Dapagliflozin, on the Risk of Heart Failure Events and Cardiovascular Death in Patients with Heart Failure and Impaired Kidney Function
  • IMPROVE-AD: IMPRoving Outcomes in Vascular DisEase- Aortic Dissection
  • POSIBIL6: Combined Dose-Finding and CV Outcomes Study With CSL300 (Clazakizumab) in Adult Subjects With ESKD Undergoing Dialysis
  • PREVENTABLE: PRagmatic Evaluation of Events and Benefits of Lipid Lowering in Older Adults
  • Test 2 Treat: A Randomized Implementation Trial to Improve LDL-C Management after Hospitalization for ASCVD
  • V-INCLUSION: Evaluating INClisiran as a soLUtion to improve LDL-C management and cloSe care gaps in an Inclusive ASCVD and ASCVD risk equivalent populatiON (VICTORION-INCLUSION)

COVID-19

  • HERO-Together Boost
  • RECOVER-AUTONOMICA Platform Protocol for Evaluation of Interventions for Autonomic Dysfunction in Post-Acute Sequelae of SARS-CoV-2 Infection
  • RECOVER-SLEEPA Platform Protocol for Evaluation of Interventions for Sleep Disturbances in Post-Acute Sequelae of SARS-CoV-2 Infection (PASC)

Hepatology

  • PAL-Liver: Introducing Palliative Care (PC) within the Treatment of End Stage Liver Disease (ESLD): A Cluster Randomized Controlled Trial

Musculoskeletal

  • SKOAP: A sequenced-strategy for improving outcomes in people with knee osteoarthritis pain

Other Drug/Treatment Evaluations

  • KALPAS: Optimizing the use of ketamine to reduce chronic postsurgical pain: Ketamine Analgesia for Long-lasting Pain After Surgery
  • MTH02: Pharmacokinetics, Pharmacodynamics, and Safety of a Single Dose Intravenous Methadone in Healthy Adult Volunteers

Pediatric

Cardiology

Pharmacokinetics

  • CUDDLE: Pharmacokinetics and Safety of Commonly Used Drugs in Lactating Women and Breastfed Infants
  • POP02: Pharmacokinetics, Pharmacodynamics, and Safety Profile of Understudied Drugs Administered to Children per Standard of Care
  • SIL02: Safety of Sildenafil in Premature Infants

Rheumatology

Surgery

  • ANA: Anesthetics and Analgesics in Children

Respiratory

  • IPF-PRO/ILD-PRO Registry: Idiopathic Pulmonary Fibrosis Prospective Outcomes (IPF-PRO) and Interstitial Lung Disease Prospective Outcomes (ILD-PRO) Registry
  • TBS02: A Prospective, Blinded, Cross-Over Trial of the Exposure-Response Relationship of Terbutaline Sulfate in Adults with Asthma