Anesthetics and Analgesics in Children

About the Study

Currently Recruiting: Participants

Study Drug/Intervention:

  • Drug: Ketorolac Tromethamine
  • Drug: Hydromorphone
  • Drug: Ketamine
  • Drug: Oxycodone
  • Drug: Morphine

Study Timeline: This study is expected to conclude in June 2025.

Visit the Study Website ID: NCT03427736


Study Objective

The purpose of this study is to characterize the pharmacokinetic (PK) and safety profile of anesthetics and analgesics in children and adolescents.

Inclusion & Exclusion Criteria

Inclusion Criteria:

  1. 0 to <18 years of age at time of enrollment (must see applicable appendix for details as not all appendices enroll across the entire age range)
  2. Parent and/or participant (if applicable) is able to understand the consent process and provides informed consent and HIPAA Authorization (if applicable)
  3. Participant provides assent as required by the institutional review board (IRB) or research ethics board (REB)
  4. Receiving one or more drugs of interest (DOI) per local standard of care
  5. Meeting DOI-specific inclusion criteria (See Appendices)

Exclusion Criteria:

  1. Known pregnancy
  2. Extracorporeal life support (i.e., ECMO, dialysis, ventricular assist device)
  3. Any condition which would make the participant, in the opinion of the investigator, unsuitable for the study


The Emmes Company, LLC

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  • PI: Kanecia Zimmerman