The ABC Science Collaborative’s latest study published in Pediatrics includes data from 20 school districts during summer 2021, when the Delta variant became the dominant strain of SARS-CoV-2 in the U.S.
A masking mandate in North Carolina schools during the early weeks of the Delta variant surge resulted in a lower rate of infection among school children and staff members than what was reported in the broader community, according to a new report from the DCRI-led ABC Science Collaborative.
Publishing in the journal Pediatrics, the analysis includes data from 20 school districts in North Carolina that held summer school or year-round school between June 14, 2021, and Aug. 13, 2021. The Delta variant became the dominant strain of SARS-CoV-2 circulating in the United States in early July 2021.
Data were submitted from 783 K-12 schools, representing 59,561 students and 11,854 staff who attended in-person. The school districts in the analysis followed the North Carolina Department of Health and Human Services (NCDHHS) StrongSchoolsNC Toolkit, which recommended, but did not require, at least three feet of physical distancing between people. The state mask mandate for K-12 settings was in effect during the study period.
The ABC Science Collaborative analyzed COVID-19 data provided by the districts. Two measures were used to estimate the spread of the Delta variant within schools: A ratio showing community-acquired cases relative to those acquired in school and the estimated secondary attack, or school-acquired infection rate.
During the study, there were 808 community-acquired cases reported vs. 64 school-acquired cases. The Delta variant has a reproductive number of about 7, meaning that, on average, in the community, one person infected with the Delta variant infects 7 others. However, in schools that implemented universal masking, for every 13 people who acquired COVID-19 outside of school, one person acquired COVID-19 within schools. As a result of COVID-19 exposure at school, 2,431 close contacts were quarantined, and 64 people acquired infections in schools, resulting in a secondary attack rate of 2.6%. This secondary attack rate is slightly higher than the secondary attack rate of approximately 1% that the ABC Science Collaborative found before the emergence of the Delta variant. This is likely due to the more infectious nature of the Delta variant.
“The findings of this study are extremely encouraging for the health and safety of students and staff attending schools where universal masking is in place,” said Kanecia Zimmerman, MD, MPH, co-chair of the ABC Science Collaborative. “The Delta variant is more transmissible than previous ancestral variants, but transmission in schools can continue to be low with vaccination among those who are eligible, strict adherence to masking, and avoidance of pandemic fatigue.”
Though the study did not allow for a comparison to an unmasked setting because a statewide mask mandate was in place, data from other schools without a mask mandate during July-August 2021 showed these schools were 3.5 times more likely to have school-associated COVID-19 outbreaks than the schools in this study that required masking.
The data from this study also highlight the importance of remaining vigilant during times throughout the school day when strict mask adherence may not be possible.
“Looking forward to the fall and winter, lunch and extracurricular activities will be areas that require additional attention to limit the transmission of COVID-19 within schools,” said Danny Benjamin, MD, PhD, MPH, co-chair of the ABC Science Collaborative. “As pediatricians and public health experts, we encourage schools to put mitigation strategies in place, such as vaccination, masking, and eating outside, to protect students and staff.”