Huiman Barnhart, PhD, O2E Program Lead. She is a member of the Duke Clinical Research Institute and a James B. Duke Distinguished Professor (effective July 1, 2024) in Duke's Department of Biostatistics and Bioinformatics. She has extensive experience in leading multicenter clinical trials (CHOIR, APPLE, PPCOS, PACTTE, STOP-DKD, COMPARE-COV, and Long COVID) and registry studies (DILIN) conducted at the Duke Clinical Research Institute (DCRI). She has been the principal investigator for multiple data coordinating centers at the DCRI. Her research interests span outcomes, endpoints, and estimands, including methods in hierarchical endpoints, SMART trials, reliability/agreement of outcomes, and performance of new medical diagnostic tests. Her collaborative areas include cardiovascular, liver, kidney diseases, and pediatric rheumatoid arthritis.