DCRI Insights

DCRI faculty member Neha Pagidipati, participates in a panel discussion at a recent conference.

DCRI Insights

Explore our comprehensive clinical research capabilities, connect with our world-class faculty and global site network, and discover opportunities to partner with us on groundbreaking research that will transform healthcare.

Continue the Conversation from AHA.25

DCRI cardiologists and operational staff eagerly dove into the latest scientific developments in cardiology with our colleagues at the American Heart Association (AHA) Scientific Sessions in New Orleans, November 7-10. Learn more about our innovative presentations and continue the insightful discussions from the conference. Join us as we continue to innovate how we treat patients and approach the most pressing research questions of our day.

The DCRI: Innovative. Efficient. Reliable.

Dr. Hernandez with a patient

About the DCRI

Academic Excellence Meets Operational Power

As an academic clinical research organization within Duke University School of Medicine, we combine practicing physicians' clinical expertise with full-service CRO capabilities. Our experts deliver innovative approaches to research challenges across all trial phases. With a trusted network spanning 1,100+ U.S. research sites and partnerships in 40+ countries, we connect sponsors to a variety of patient populations. From our founding in 1969, we've pioneered methodologies that define modern clinical research while delivering results that advance medicine and improve lives globally.

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Solutions & Services

Extensive, Integrated Clinical Trial Capabilities

From Phase I through post-marketing research, we deliver comprehensive clinical trial management tailored to your needs. Our innovative approach includes adaptive study designs, pragmatic and decentralized trial components, and specialized services like digital health solutions, advanced analytics, and safety surveillance. With decades of experience executing complex trials, we provide accelerated startup timelines, proactive site management, and FDA-ready data analysis that transforms promising therapies into approved treatments.

DCRI faculty member Danny Benjamin speaks with a pediatric patient.

Therapeutic Expertise

Deep Expertise Across Critical Therapeutic Areas

Although best known for our pioneering cardiology research, our experts also lead groundbreaking clinical trials and studies in gastrointestinal health, infectious diseases, neuroscience, oncology, pediatrics, and respiratory medicine. As practicing physicians, our researchers design trials grounded in patient needs and understand the unique regulatory and operational challenges of each specialty. This therapeutic depth, combined with access to Duke University's genomics and proteomics capabilities, ensures studies advance the fundamental understanding of health and disease.

DCRI faculty member Pamela Douglas speaks on a panel at a recent conference.

Faculty Leadership

World-Renowned Clinical Research Leaders

Our 100+ faculty members are global authorities in clinical research, serving as principal investigators and steering committee members for major industry trials. These practicing physicians provide scientific leadership across multiple therapeutic areas while offering invaluable insights into FDA regulatory pathways and clinical development strategies. With over 40 years of innovative research experience and 23,000+ peer-reviewed publications, our faculty understand the operational, financial, and regulatory implications of diverse project designs, ensuring optimal outcomes for sponsors.

Five DCRI fellows stand together smiling at a conference alongside one of their DCRI faculty mentors.

Fellowship Program (Postdoctoral)

Training Tomorrow's Clinical Research Leaders

Our postdoctoral fellowship program has trained over 300 clinical researchers across numerous therapeutic areas. Fellows collaborate directly with expert faculty mentors on multi-center trials and registries while pursuing advanced degrees. With exceptional access to extensive clinical databases, weekly seminars, and major scientific meetings, participants develop advanced research management skills and achieve high levels of research productivity. We provide comprehensive support for career development, whether you are pursuing roles in academia, industry, or research leadership.

A doctor interacts with a young patient sitting on their mother's lap.

Recruiting Sites & Participants

Join Our Global Research Network

We're actively recruiting participants and site partners for groundbreaking studies across multiple therapeutic areas. With approximately 1,100 research sites throughout North America and partnerships worldwide, we foster collaboration among research sites, community partners, patients, and study teams. Our extensive network of academic medical centers and community-based practices enables us to identify high-performing sites and engage key patient populations. Partner with us to address current medical care challenges through safe, inclusive, and efficient clinical research.

Duke University: Amplifying DCRI's Capabilities

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DCRI is integrated into Duke's extraordinary biomedical enterprise, which includes 2,600+ faculty, $1B+ in annual research, and 70+ shared service centers. This powerful ecosystem of research, from early-phase trials to health system-wide studies, enhances our ability to accelerate innovation at scale.

Find & Connect With DCRI Experts

Join us at upcoming conferences and scientific meetings where our faculty and operational leaders share groundbreaking research, forge strategic partnerships, and advance the future of clinical trials. Our team regularly participates in premier industry events worldwide, presenting innovative methodologies, discussing therapeutic breakthroughs, and exploring collaboration opportunities with sponsors, sites, and research partners. 

Click the event highlights below to learn where you can find us, or contact the DCRI to discuss how you can leverage our expertise.

SCOPE Summit

to

Rosen Shingle Creek, Orlando, FL

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DCRI’s Podcast: Beyond the Endpoint

Tune in every other Wednesday as DCRI’s Manesh Patel, MD, and Emily O’Brien, PhD, demystify clinical research and healthcare through engaging conversations with leading clinicians and scientists. Listen on all major platforms as they explore timely topics, including the intersection of politics and medicine, hypertension, autism, AI in healthcare, and global headlines shaping the future of research and medicine.

Listen Now

Interested in collaborating with the DCRI? Contact Us.