News Archive

The EXSCEL trial, which explored the impact of exenatide on major cardiovascular events in patients with Type 2 diabetes, has also published nearly a dozen secondary manuscripts on a range of topic

The observational study found that amongst acute ischemic stroke patients treated with intravenous tissue plasminogen activator, patients who had experienced a previous stroke within the past two w

A new analysis from the DCRI showed that 35 percent of direct costs related to musculoskeletal pain were attributable to about 4 percent of patients who were persistent high-cost utilizers.

The survey focused on invasive cardiac care and measured patient knowledge, goals, and concerns related to these procedures.

Study results recently published in Neuropsychopharmacology indicate that young adults with ADHD are at higher risk of becoming addicted to nicotine after even the first exposure to the substance. The study included 136 non-smokers between ages 18 to 25, about half of whom had a clinical diagnosis of ADHD. Participants were administered two different doses of nicotine and a placebo.

Recent results from DAPA-HF may be moving the treatment of heart failure into a new era of “quadruple therapy,” but further studies are needed to understand the benefits of using an SGLT2 inhibitor such as dapagliflozin in addition the guideline-recommended triple therapy, wrote the DCRI’s Michael Felker, MD, in a recent editorial in Circulation.

A study of proteins in plasma taken from patients in the IPF-PRO registry found that patients with IPF have a distinct circulating set of proteins and that select proteins correlate well with clini

Data monitoring committees (DMCs) play a critical role in clinical trials by protecting patients—especially in studies involving high-risk populations or potentially harmful treatments—and in order to fulfill this role successfully, these committees should have access to all data at each interim review, wrote the authors of a recent paper published in the Annals of Internal Medicine.

A new analysis of a DCRI study revealed that younger patients and older patients may need to undergo different types of testing for coronary artery disease in order to more accurately predict risk.

The DCRI served as the statistical and data coordinating center for ISCHEMIA, a late-breaking clinical trial that indicated invasive heart procedures may not reduce the chance of experiencing a maj