ADHD Could Present Higher Risk for Nicotine Addiction
Study results recently published in Neuropsychopharmacology indicate that young adults with ADHD are at higher risk of becoming addicted to nicotine after even the first exposure to the substance. The study included 136 non-smokers between ages 18 to 25, about half of whom had a clinical diagnosis of ADHD. Participants were administered two different doses of nicotine and a placebo.
New Quadruple Therapy Shows Promise, But More Data are Needed
Recent results from DAPA-HF may be moving the treatment of heart failure into a new era of “quadruple therapy,” but further studies are needed to understand the benefits of using an SGLT2 inhibitor such as dapagliflozin in addition the guideline-recommended triple therapy, wrote the DCRI’s Michael Felker, MD, in a recent editorial in Circulation.
Proteins in Plasma Could Provide Information about IPF Disease Severity
A study of proteins in plasma taken from patients in the IPF-PRO registry found that patients with IPF have a distinct circulating set of proteins and that select proteins correlate well with clini
Data Monitoring Committees Need Complete Data to Protect Patients
Data monitoring committees (DMCs) play a critical role in clinical trials by protecting patients—especially in studies involving high-risk populations or potentially harmful treatments—and in order to fulfill this role successfully, these committees should have access to all data at each interim review, wrote the authors of a recent paper published in the Annals of Internal Medicine.
AHA 2019: Data Highlight Differences in Discrimination of Noninvasive CAD Testing
A new analysis of a DCRI study revealed that younger patients and older patients may need to undergo different types of testing for coronary artery disease in order to more accurately predict risk.
DCRI Contributes to Important Results Presented at AHA 2019
The DCRI served as the statistical and data coordinating center for ISCHEMIA, a late-breaking clinical trial that indicated invasive heart procedures may not reduce the chance of experiencing a maj
DCRI Researchers Weigh In On Wearables in Heart Failure Care
Researchers from the DCRI are optimistic about the opportunities that wearable devices present in caring for patients with heart failure; however, they also recognize that challenges must be overcome to successfully interpret and act upon patient data collected from wearables.
Tool to Assess Cardiovascular Risk May be Inaccurate in Older Adults
A DCRI-led study is the first to test the performance of the Pooled Cohort Risk Equations, a commonly used tool for assessing cardiovascular risk, in older adults.
DCRI Pediatrician Contributes to Guidance on Pediatric Weight-Loss Surgery
The DCRI’s Sarah Armstrong, MD, served as the lead author for a policy statement and a co-author on a technical report advocating for more widespread use of bariatric and metabolic surgeries for ch
Study Suggests Strokes May be Treated Differently than Heart Attacks
A recent study from DCRI researchers found that patients who have had strokes may receive different care than those who have had heart attacks, despite evidence that shows statins are effective for secondary prevention in both populations to prevent recurring ischemic events.