PROVIDE-HF Finds Early Improvements in Quality of Life in Patients with Heart Failure Treated with Sacubitril/Valsartan
By evaluating patient-reported and electronic health record data, the pragmatic clinical study adds important real-world evidence to inform clinical practice.
DCRI Selected as U.S. Coordinating Center for NIH ACTIV-1 Trial
The DCRI has received $44 million in funding to examine whether three immune modulators help prevent overactive immune response in moderate or severe cases of COVID-19.
TCT 2020: New One-year Follow Up Results Shed Light on Optimal Care After PCI
New results from the one-year follow up of the DEFINE-PCI trial shed light on how to optimize care for patients who have undergone percutaneous coronary intervention (PCI). The results, presented as late-breaking science by DCRI’s Manesh Patel, MD, were shared virtually Thursday at the 2020 Transcatheter Cardiovascular Therapeutics (TCT) Connect.
Clinical Trials ‘System is Working,’ Hernandez Says
Recent pauses of COVID-19 vaccine trials show that the clinical trials system is working, writes DCRI Executive Director Adrian Hernandez, MD, MHS, in an opinion piece published today by STAT News. Hernandez authored the piece in response to pauses of three vaccine trials: First AstraZeneca’s study was put on hold in September, and this week, both Johnson & Johnson and the NIH paused trials.
DCRI Launches First Direct-to-Family Study to Improve Medication Dosing and Adherence in Children and Teens with Lupus
The clinical study's home-based design combines on-site nursing visits and mobile technology to embed research into patients' lives.
At DCRI, Collaborations Lead to Better Evidence
Building on DCRI’s strong history in building cardiovascular evidence, researchers at the Institute with a wide range of expertise are also considering how cardiovascular disease factors into other
ESC 2020: Randomized Trial Confirms ACEI/ARB Safety for Patients with COVID-19
EDITORS' NOTE: This story was updated January 19, 2021 when the study was published in Journal of the American Medical Association.
ESC 2020: DCRI Successfully Conducts Trial in FDA-Catalyst and Sentinel System
The IMPACT-AFib trial lays the groundwork for future large-scale trials to be conducted using electronic claims data.
ESC 2020: ADAPTABLE Presents Opportunities, Underscores Challenges for Pragmatic Research
DCRI Executive Director Adrian Hernandez, MD, MHS, called for a platform that will enable clinical research to be embedded into patient care, allowing research to be conducted at patients’ homes.
ESC 2020: DCRI Analysis Sheds New Light on Management of Ischemic Heart Disease and Heart Failure
The ISCHEMIA trial made headlines last year at the American Heart Association 2019 Scientific Sessions, where primary results were presented indicating that invasive heart procedures may not reduce