The Durham Centre, the office building where the DCRI is housed, is shown set against a sunset sky. Durham Centre photo credit: Discover Durham

Innovative. Efficient. Reliable.

The Duke Clinical Research Institute (DCRI), part of the Duke University School of Medicine, is the largest full-service, mission-driven academic clinical research organization. We combine insights from practicing physicians in a world-class health system with unmatched data science expertise and an end-to-end operations infrastructure. Our model ensures studies and trials of all sizes run effectively, achieve the best outcomes, and transform health care for our patients and people everywhere.
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Clinical Trials and Studies of All Sizes

The DCRI conducts Phase II-IV clinical trials with an extensive U.S. site network, supported by worldwide partnerships and flexible models for global studies.
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Reimagined, Innovative Clinical Research 

We design "research for all" that can be embedded in clinical practice and community settings, while our biostatisticians and data scientists define and use best-in-class methodologies.
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Post-Approval Research to Accelerate Adoption

Our experts lead observational studies and real-world data analysis with the goal of integrating research findings into clinical practice and improving the standard of care nationally and globally.

DCRI News

Stay informed of research news regarding our thought leaders, collaborations, and partnerships.

Durham Centre photo credit: Discover Durham