Duke University has been awarded $12.9 million from the Patient-Centered Outcomes Research Institute (PCORI) for a new clinical trial aimed at improving the standard of care for autistic children with chronic digestive discomfort.

Advanced liver disease (ALD) occurs when significant scarring causes the liver to lose function. Patients with ALD often have serious health challenges but have limited access to palliative care that could improve their quality of life. A new multicenter trial demonstrates a new approach that could potentially transform access to palliative care for patients with ALD and address a major care gap.

A new publication authored by the Precision Health Alliance, a consortium sponsored and coordinated by the Duke Clinical Research Institute (DCRI), stresses the need for an unprecedented degree of collaboration across the scientific community. According to the authors, this level of cooperation is essential to ensure that gene editing interventions are patient-centered, safe, and ethical.