News Archive

If you want to change patient and provider behavior to improve a patient’s health, will an informational mailer make a difference?

A large randomized, placebo-controlled clinical trial led by the National Institutes of Health with support from the Duke Clinical Research Institute shows that treating adults hospitalized with COVID-19 with infliximab or abatacept – drugs widely used to treat certain autoimmune diseases – substantially improved clinical status and reduced deaths.

A recent paper from Duke Clinical Research Institute (DCRI) faculty on behalf of the American Gastroenterological Association (AGA) provides new tools for health care providers treating patients wi

A new study set out to determine the prevalence of tPA declination in a nationwide registry of acute ischemic stroke (AIS) patients and to investigate differences in declination by race-ethnicity. The results appear in a paper in the February 28 issue of Neurology entitled ‘Race-Ethnic Disparities in Rates of Declination of Thrombolysis for Stroke.’

A recent publication reports on an analysis of how study-specific fitness-for-use was addressed amongst pragmatic clinical trials that utilize real-world data (RWD), and makes recommendations to de

COVID-19 health care workers experienced high rates of potential moral injury that are comparable to rates among military veterans, according to a collaborative study between Duke University, Vanderbilt University, and the Department of Veterans Affairs (VA).

Heart failure patients taking the investigational drug omecamtiv mecarbil, which has been previously shown to improve long-term outcomes, see little impact on their ability to exercise compared to a placebo, according to a study supported by the Duke Clinical Research Institute.

A new type of anti-clotting drug caused fewer bleeding incidents among patients with atrial fibrillation than the commonly prescribed apixaban, according to results from a head-to-head comparison of the two. The study, led by cardiologists at the DCRI, was reported April 3 at the American College of Cardiology annual scientific sessions meeting and simultaneously published in the journal The Lancet.

Less than half of the patients with first-detected atrial fibrillation (AFib) receive rhythm control at admission, according to data analysis from the nationwide Get With The Guidelines®-Atrial Fib

School districts that required masking saw lower rates of COVID-19 transmission within schools last fall compared to those with optional masking policies, according to a study by the ABC Science Collaborative.