Patients have Fewer Severe Asthma Attacks if Provided with Patient-Centered Intervention
A pragmatic, open-label, randomized trial of 1,201 patients found as-needed use of inhaled glucocorticoids plus existing therapy improved asthma outcomes in a broad population of Black and Latinx patients with poorly controlled asthma.
With ‘Test-to-Stay,’ Children and Staff Can Safely Remain in School After COVID Exposures
Top scientists and physicians from the ABC Science Collaborative outline how a more focused COVID-19 “test-to-stay” protocol can keep kids in school without overwhelming the system.
Patient Survey Finds Post-operative Pain Common After Total Joint Replacement Surgery
A survey of 2,638 Duke Health patients who had total replacement of knee, hip, or shoulder joints in 2014-20 found that approximately one-third experienced high-impact or bothersome chronic pain fo
Data Finds Universal Masking Limits School Transmission of COVID-19 Despite Delta Variant
The ABC Science Collaborative’s latest study published in Pediatrics includes data from 20 school districts during summer 2021, when the Delta variant became the dominant strain of SARS-CoV-2 in th
PRONOUNCE Trial Highlights Need for Rigorously Conducted Cardio-oncology Trials to Better Define Cardiovascular Risk of New Cancer Agents
The trial, which was terminated early due to slow enrollment and low number of events, did not conclusively show whether different modes of a common treatment for prostate cancer were associated wi
Different Paths, Similar Learnings from Two DCRI Virtual Trials
Research conducted remotely presents a number of benefits to clinical research—along with unique challenges.
ABC Science Collaborative Finds Schools Are Safe, Even During COVID-19 Winter Surge; Transmission is Higher for Extracurricular Events Such as Sports
Despite a surge in community cases in winter 2020, within-school transmission remained low, with most transmission within high schools occurring in school-sponsored sports. New data analyzed and published by the DCRI-led ABC Science Collaborative sheds new light on school safety during a COVID-19 surge and reinforces the message that masking is an effective strategy to mitigate within-school transmission.
Increasing Health Care System Participation in Research Requires New Support Systems
DCRI Executive Director Adrian Hernandez, MD, MHS, and co-authors recently published a commentary in the New England Journal of Medicine advocating for new ways to incentivize health care systems t
Report Shows that N.C. K-12 Schools Reopened Safely, Paving the Way for Schools Nationwide to Limit COVID-19 Spread in the Classroom
Top scientists and physicians from the ABC Science Collaborative have shared insights from North Carolina schools, coupled with a science-based blueprint for all schools to resume full, in-person instruction safely. A new report issued today by the DCRI-led ABC Science Collaborative shows that North Carolina schools were highly successful in preventing the transmission of COVID-19 within school buildings and offers science-based learnings for the nation’s schools to limit COVID-19 spread.
Randomized, Pragmatic Trial Testing Antimicrobial Therapy for Treatment of Idiopathic Pulmonary Fibrosis Shows No Significant Effect
A large pragmatic study in idiopathic pulmonary fibrosis (IPF) found that antimicrobial therapy did not have a statistically significant effect on respiratory hospitalization or death compared with usual care alone.