ADHD Could Present Higher Risk for Nicotine Addiction
Study results recently published in Neuropsychopharmacology indicate that young adults with ADHD are at higher risk of becoming addicted to nicotine after even the first exposure to the substance. The study included 136 non-smokers between ages 18 to 25, about half of whom had a clinical diagnosis of ADHD. Participants were administered two different doses of nicotine and a placebo.
Research Network Based at DCRI Awarded up to $102.5M for Work on Antibacterial Resistance
The Antibacterial Resistance Leadership Group conducts clinical research to better understand how to diagnose, treat, and prevent antibacterial resistant infections.
Working at the Intersection of Expertise to Improve Patient Care
With eight-plus clinical areas under one roof, the DCRI enables faculty members of various specialties to work together to draw deeper insights in clinical research and find better treatments for patients.
New Quadruple Therapy Shows Promise, But More Data are Needed
Recent results from DAPA-HF may be moving the treatment of heart failure into a new era of “quadruple therapy,” but further studies are needed to understand the benefits of using an SGLT2 inhibitor such as dapagliflozin in addition the guideline-recommended triple therapy, wrote the DCRI’s Michael Felker, MD, in a recent editorial in Circulation.
Proteins in Plasma Could Provide Information about IPF Disease Severity
A study of proteins in plasma taken from patients in the IPF-PRO registry found that patients with IPF have a distinct circulating set of proteins and that select proteins correlate well with clini
To Leverage Power of Machine Learning, Focus on Implementation is Needed
With machine learning on the rise, DCRI’s Eric Peterson, MD, MPH, takes a retrospective look at prior efforts to implement risk prediction models and what lessons can be drawn from the past for cur
AHA 2019: DCRI Study Tests Apixaban versus Warfarin in New Patient Population
Apixaban may be a reasonable treatment option for patients with atrial fibrillation who also have renal disease and are receiving hemodialysis, according to late-breaking clinical trial results from RENAL-AF presented Saturday, Nov. 16 at the American Heart Association Scientific Sessions 2019.
DCRI Faculty Recognized on Global “Highly Cited” List
Fifty-four researchers from Duke, including nine from the DCRI, were recognized for their high citation rates.
Data Monitoring Committees Need Complete Data to Protect Patients
Data monitoring committees (DMCs) play a critical role in clinical trials by protecting patients—especially in studies involving high-risk populations or potentially harmful treatments—and in order to fulfill this role successfully, these committees should have access to all data at each interim review, wrote the authors of a recent paper published in the Annals of Internal Medicine.
AHA 2019: Data Highlight Differences in Discrimination of Noninvasive CAD Testing
A new analysis of a DCRI study revealed that younger patients and older patients may need to undergo different types of testing for coronary artery disease in order to more accurately predict risk.