DCRI to Partner with Novo Nordisk on Large-Scale Global Cardiovascular Study in Acute Myocardial Infarction
By randomizing 10,000 adult patients, ARTEMIS will evaluate the effects of a study medicine versus placebo on cardiovascular outcomes in patients with acute myocardial infarction.
Antibiotic Shows Effectiveness Against Deadly Staph Infections
An antibiotic that has shown effectiveness for bacterial pneumonia also appears successful in fighting methicillin-resistant staph infections, reports a team led by Duke Health. The drug, ceftobiprole, showed similar benefit when tested against the antibiotic daptomycin to treat complicated Staphylococcus aureus bacterial infections. If approved by the FDA, ceftobiprole could provide another line of defense against a common and often deadly bacterial infection.
Hispanic Heritage and Language Influence COVID-19 Testing and Vaccination
When it comes to COVID-19 testing and vaccination, not all Hispanic populations respond the same.
"Click and Mortar" Opportunities for Digitization and Consumerism in Trials
Explore how the integration of digital tools and consumer-oriented approaches in clinical trials can enhance participant diversity and recruitment efficiency while addressing challenges in equity, ethics, and security.
The Doctor Who Wants to Change How We Treat Cardiovascular Disease
Cardiovascular disease is the number one killer of people in the United States and worldwide. Yet physicians often do not prescribe evidence-based medicines that could change those statistics.
ACTIV-6 trials show no benefit to fluticasone furoate for COVID-19 symptoms
A study led by the Duke Clinical Research Institute (DCRI) in partnership with Vanderbilt University found no clinical benefit to taking fluticasone furoate for treatment of mild-to-moderate COVID-19 symptoms.
CardioHealth Alliance Study Aims to Assess How to Improve Cholesterol Management in Patients with ASCVD
CardioHealth Alliance is announcing a new project sponsored by Amgen aimed at assessing and gathering data regarding how to improve quality of care among patients hospitalized for ASCVD. This work, referred to as the “Test to Treat” project, will be led by cardiovascular disease prevention specialist and DCRI faculty member Neha Pagidipati, MD, MPH.
New Blood Test Detects a Key Indicator of Parkinson’s Disease
Researchers have developed a blood test that detects Parkinson’s disease, potentially establishing a way to help diagnose the condition before nervous system damage worsens. A new blood-based diagnostic test would be a major advancement for Parkinson’s disease, which afflicts 10 million people worldwide and is the second-most common neurodegenerative disease after Alzheimer’s. Led by a team of Duke Health neuroscientists, the study appears Aug. 30 in the journal Science Translational Medicine.
Intravenous Iron Treatment Provides Some Benefit to Patients with Heart Failure and Iron Deficiency
Despite numerical improvements in mortality, hospitalizations and exercise ability, data did not reach the pre-specified level of statistical significance.
Newly published research explores impact of COVID-19 on hospitalized infants
Newly published research led by the Pediatrix Medical Group and the Duke Clinical Research Institute’s Rachel Greenberg, MD, MB, MHS assessed the impact of COVID-19 on pregnant women and infants admitted to the neonatal intensive care unit (NICU). It is believed to be the largest study evaluating the prevalence of COVID-19 within a diverse neonatal population and associated hospital outcomes.