Innovative Heart Failure Trial Infrastructure Serves as Model for Future Pragmatic Studies
The SPIRRIT-HFpEF trial, being led by Sweden’s Karolinska Institutet and the U.S.’s Duke Clinical Research Institute, is a randomized pragmatic clinical trial of spironolactone or eplerenone vs usu
Indications of Moral Injury Similar between Combat Veterans and COVID-19 Health Care Workers
COVID-19 health care workers experienced high rates of potential moral injury that are comparable to rates among military veterans, according to a collaborative study between Duke University, Vanderbilt University, and the Department of Veterans Affairs (VA).
ACC22: CAMEO Registry study reveals major variations in clinical cangrelor use compared with trials
Less than 30% of heart attack patients treated with cangrelor received the treatment in a way that was consistent with established protocols and the drug’s FDA labeling, according to new research from the Duke Clinical Research Institute using the CAMEO registry.
ACC22: Few Patients Have Infected Heart Devices Removed Despite Lifesaving Benefits
Medicare patients whose implantable heart devices became infected were less likely to die from the complication if they had the hardware removed compared to patients who only received antibiotics, according to the largest study on the topic, led by the Duke Clinical Research Institute.
ACC22: Investigational Anti-Clotting Drug Reduces Bleeding Risk Among AF Patients
A new type of anti-clotting drug caused fewer bleeding incidents among patients with atrial fibrillation than the commonly prescribed apixaban, according to results from a head-to-head comparison of the two.
ACC22: Investigational Drug for Heart Failure has Little Impact on Exercise Tolerance
Heart failure patients taking the investigational drug omecamtiv mecarbil, which has been previously shown to improve long-term outcomes, see little impact on their ability to exercise compared to a placebo, according to a study supported by the Duke Clinical Research Institute.
New Analysis Presents Snapshot of Management of Patients Hospitalized with a First Episode of Atrial Fibrillation
Less than half of the patients with first-detected atrial fibrillation (AFib) receive rhythm control at admission, according to data analysis from the nationwide Get With The Guidelines®-Atrial Fib
Universal Masking in Schools is Shown to Reduce Spread of COVID-19
School districts that required masking saw lower rates of COVID-19 transmission within schools last fall compared to those with optional masking policies, according to a study by the ABC Science Collaborative.
Black and Latinx Patients have Fewer Severe Asthma Attacks if Provided with Patient-Centered Intervention
A pragmatic, open-label, randomized trial of 1,201 patients found as-needed use of inhaled glucocorticoids plus existing therapy improved asthma outcomes in a broad population of Black and Latinx patients with poorly controlled asthma.
Healthcare Workers Twice as Likely to Vaccinate Children Under 5 Immediately
Healthcare workers who have children under age 5 are twice as likely as other parents to plan to vaccinate their children against COVID-19, according to a new poll conducted by the HERO Registry coordinated by the Duke Clinical Research Institute.