Advanced liver disease (ALD) occurs when significant scarring causes the liver to lose function. Patients with ALD often have serious health challenges but have limited access to palliative care that could improve their quality of life. A new multicenter trial demonstrates a new approach that could potentially transform access to palliative care for patients with ALD and address a major care gap.

A new publication authored by the Precision Health Alliance, a consortium sponsored and coordinated by the Duke Clinical Research Institute (DCRI), stresses the need for an unprecedented degree of collaboration across the scientific community. According to the authors, this level of cooperation is essential to ensure that gene editing interventions are patient-centered, safe, and ethical. 

A major pragmatic clinical trial published this month in JAMA Network Open offers new insight into how the U.S. health system can support Veterans living with chronic low back pain—one of the most common and disabling conditions affecting former service members.

The Duke Clinical Research Institute (DCRI) faculty and operational experts presented or contributed to research across over 70 sessions at the American College of Cardiology Scientific Sessions (ACC.26), held March 28–30 in New Orleans. Their thought leadership encompassed featured presentations, late-breaking clinical trials, moderated debates, digital poster forums, and expert panel discussions as they shared new data, debated emerging evidence, and offered practical guidance on clinical care.