Patient Survey Finds Post-operative Pain Common After Total Joint Replacement Surgery
A survey of 2,638 Duke Health patients who had total replacement of knee, hip, or shoulder joints in 2014-20 found that approximately one-third experienced high-impact or bothersome chronic pain fo
Lung Transplant Clinical Trials Network Renewed for Seven More Years
With $21 million in new funding from the NIAID, the network now includes eight centers in North America and will study adolescent lung transplant recipients as well as adult.
DCRI Think Tank Considers Promise of Machine Learning in Clinical Evidence Generation
Stakeholders at a January 2020 DCRI Think Tank examined the role of machine learning (ML) in the design, conduct, and analysis of clinical trials.
New Heart Clinical Trial to Shine Light on Early Atrial Fibrillation Treatment
Until now, scientific research about treatment for the most common type of heart arrythmia, atrial fibrillation (AFib), has primarily focused on patients with already established cases of the condition. CHANGE AFib, a new pragmatic clinical trial, will determine whether early treatment with the antiarrhythmic drug dronedarone improves cardiovascular and long-term outcomes in patients presenting to the hospital with first-detected AFib.
CSRC Pilot Project Creates Novel Pediatric ECG Data Warehouse
A new project led by the Cardiac Safety Research Consortium created a first-in-kind data warehouse to help ensure comprehensive cardiac safety review for therapeutic product development for children.
Data Finds Universal Masking Limits School Transmission of COVID-19 Despite Delta Variant
The ABC Science Collaborative’s latest study published in Pediatrics includes data from 20 school districts during summer 2021, when the Delta variant became the dominant strain of SARS-CoV-2 in th
Pediatrician, Policy Expert, & School Principal
The below is a republication of a story that featured DCRI’s Charlene Wong, MD, MSHP, which appeared in Duke University School of Medicine’s digital publication, Magnify.
New Pragmatic Trial Seeks to Improve Care for Lower Back Pain
DCRI principal investigators lead the clinical and data coordinating centers for a new study that will evaluate a model of care that centers on non-pharmacological treatment options.
New CardioHealth Alliance Established to Expedite Evidence-Based Solutions for Prevention and Care of Cardiovascular, Renal and Metabolic Diseases
A new consortium called the CardioHealth Alliance will bring together a multi-disciplinary group of experts to improve the care and health of patients across cardiovascular, renal, and metabolic diseases. The alliance, which was established by leaders from the Duke Clinical Research Institute (DCRI) and the Stanford Center for Clinical Research (SCCR), welcomes Novartis Pharmaceuticals Corporation (“Novartis”) as a founding member and initial funding partner and invites clinicians, patients, data scientists, health care leaders, and policy makers to partner to improve disease care pathways and expedite the implementation of evidence into practice.
HFSA 2021: Digital Tools Could Help Improve Patient Self-Care
An ancillary study found improvements in a composite heart failure quality score after patients used a mobile app to help them manage their heart failure.