News Archive

Through new ways of working and collaborations across Duke, the DCRI’s Clinical Events Classification group is continuously improving on its processes.

The study, which is the only randomized trial testing rixaroxaban in this patient population, builds on previous evidence established by the DCRI-led ROCKET-AF and ARISTOTLE studies.

Patients assigned to the treatment, omecamtiv mecarbil, experienced a statistically significant difference in a composite endpoint of time to cardiovascular death or time to first heart failure event.

By evaluating patient-reported and electronic health record data, the pragmatic clinical study adds important real-world evidence to inform clinical practice.

The DCRI has received $44 million in funding to examine whether three immune modulators help prevent overactive immune response in moderate or severe cases of COVID-19.

New results from the one-year follow up of the DEFINE-PCI trial shed light on how to optimize care for patients who have undergone percutaneous coronary intervention (PCI). The results, presented as late-breaking science by DCRI’s Manesh Patel, MD, were shared virtually Thursday at the 2020 Transcatheter Cardiovascular Therapeutics (TCT) Connect.

Recent pauses of COVID-19 vaccine trials show that the clinical trials system is working, writes DCRI Executive Director Adrian Hernandez, MD, MHS, in an opinion piece published today by STAT News. Hernandez authored the piece in response to pauses of three vaccine trials: First AstraZeneca’s study was put on hold in September, and this week, both Johnson & Johnson and the NIH paused trials.

The clinical study's home-based design combines on-site nursing visits and mobile technology to embed research into patients' lives.

Building on DCRI’s strong history in building cardiovascular evidence, researchers at the Institute with a wide range of expertise are also considering how cardiovascular disease factors into other

EDITORS' NOTE: This story was updated January 19, 2021 when the study was published in Journal of the American Medical Association.