DCRI Think Tanks: Recent Publications

Leading experts recently explored how generative AI could revolutionize clinical research through automated documentation and enhanced trial efficiency. Their findings, published in JACC: Advances, outline crucial steps for successful AI integration while addressing technical, ethical, and regulatory challenges to ensure more inclusive and equitable research outcomes.

Healthcare leaders have united to tackle the mounting challenges of expensive and inefficient drug development in an era of rising healthcare costs and aging populations. Their recommendations, published in the Journal of Clinical and Translational Science, chart a path toward more equitable, efficient, and inclusive clinical trials that better serve diverse communities.

Read insights from a recent DCRI Think Tanks where experts discussed the current state of drug development for chronic health conditions, identified key barriers, and formulated six action items to accelerate drug development.

A recent publication in the journal Clinical Infectious Diseases highlights key takeaways from a DCRI Think Tank centered on the insights gained from the COVID-19 pandemic and 10 key steps on how this acquired knowledge can help inform the next pandemic response.

Explore how the integration of digital tools and consumer-oriented approaches in clinical trials can enhance participant diversity and recruitment efficiency while addressing challenges in equity, ethics, and security.

An industry emphasis on improving inclusion and diversity in clinical trials continues to grow, but strategies to achieve more balanced representation in research and clinical care remain elusive.

Stakeholders at a January 2020 DCRI Think Tank examined the role of machine learning (ML) in the design, conduct, and analysis of clinical trials. Key areas of clinical trial methodology were identified where ML holds particular promise and priority areas for further investigation.

A “validity argument” approach takes into account that the context of each trial is different and attempts to overcome barriers historically associated with measuring and reporting patient-reported outcomes in clinical trials.

A wide range of stakeholders who attended an April 2019 DCRI Think Tank helped to identify current challenges to developing treatments for chronic kidney disease, as well as make recommendations for strategies to address these challenges.

Attendees to a January 2019 DCRI Think Tank outlined recommendations for optimizing pragmatic clinical trials and weighing risks and benefits of innovative trial designs.